Trusted Scientific Resources on Rare Diseases Research

At Travere Global Medical Affairs, we are dedicated to scientific exchange, including sharing up-to-date scientific insights and resources with healthcare professionals.

The goal is to provide educational resources ranging from publications and expert-led podcasts to recent congress data and relevant medical information.

About us

Travere at ASN Kidney Week 2025

American Society of Nephrology (ASN) Kidney Week 2025

Kidney Week 2025 is the annual meeting of the American Society of Nephrology (ASN). Travere Therapeutics was excited to participate in ASN Kidney Week 2025 and engage with nephrology leaders from around the world.

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MA-DS-25-0077 | November 2025

New 2025 IgAN/IgAV Guidelines from KDIGO

On September 18, 2025, the Kidney Disease Improving Global Outcomes (KDIGO) organization released the KDIGO 2025 Clinical Practice Guideline for the Management of IgA Nephropathy and IgA Vasculitis.

Marking a turning point in glomerular disease care, the new guidelines incorporate evidence from randomized controlled trials through August 2024.

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MA-DS-25-0096 | September 2025

Risk Evaluation and Mitigation Strategies (REMS) Update for Sparsentan

On August 27, 2025, the Risk Evaluation and Mitigation Strategies (REMS) requirements for sparsentan were updated to reduce the frequency of liver function monitoring to every three months and to remove the embryo-fetal toxicity REMS monitoring requirement.

For more information, please read the US Prescribing Information.

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MA-SP-25-0127 | September 2025

Travere at GlomCon Hawaii 2025

GlomCon Hawaii 2025

GlomCon Hawaii is the annual conference of the GlomCon Foundation. Travere Therapeutics was honored to participate and engage with clinicians, researchers, and nephrology experts from around the world.

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MA-DS-25-0086 | September 2025

Webinar

The Dual Impact of Sparsentan on Inflammation and Proteinuria in IgA Nephropathy

Travere partnered with GlomCon on one of their Clinical Trial Series webinars. This webinar focused on sparsentan in IgA nephropathy.

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MA-SP-25-0139 | November 2025

Explore our science

Publication NephrologyIgAN

Efficacy and Safety of Sparsentan Versus Irbesartan in Patients with IgA Nephropathy (PROTECT): 2-Year Results From a Randomised Active-Controlled Phase 3 Trial

The Lancet – 2023

Publication NephrologyFSGSIgAN

Mechanism of Protective Actions of Sparsentan in the Kidney: Lessons From Studies in Models of Chronic Kidney Disease

Clinical Science – 2024

Publication NephrologyFSGSIgAN

Sparsentan. Dual Angiotensin II AT1 Receptor Blocker and Endothelin ETA Receptor Antagonist, Treatment of Focal Segmental Glomerulosclerosis, Treatment of IgA Nephropathy

Drugs of the Future – 2020

Publication NephrologyFSGS

Sparsentan for Focal Segmental Glomerulosclerosis in the DUET Open-Label Extension: Long-term Efficacy and Safety

Kidney Medicine – 2024

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Summary NephrologyIgAN

Implications of Proteinuria Remission on Estimated Glomerular Filtration Rate Trajectory in Patients With IgA Nephropathy in PROTECT

American Society of Nephrology (ASN) Kidney Week – 2024

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Summary NephrologyIgAN

Sparsentan as First-Line Treatment of Incident Patients With IgA Nephropathy (IgAN): Interim Analysis of the SPARTAN Trial

American Society of Nephrology (ASN) Kidney Week 2024 – 2024

Summary NephrologyIgAN

Sparsentan (SPAR) Added to Stable Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2is) in Adults With IgA Nephropathy (IgAN) in the Phase 2 SPARTACUS Trial

62nd European Renal Association (ERA) Congress 2025 – 2025

Summary NephrologyFSGS

Patients in DUPLEX Achieved Partial or Complete Remission of Proteinuria Earlier and More Often With Sparsentan vs Irbesartan: Implications for Slowing Progression to Kidney Failure in Focal Segmental Glomerulosclerosis (FSGS)

National Kidney Foundation (NKF) Spring Clinical Meetings 2025 – 2025

See all posters & presentations

Travere and National Kidney Foundation Collaboration

Podcast Episode NephrologyFSGSIgAN

Life as a Nephrology Professional – Milestones in IgAN & FSGS: Advancing Understanding and Possibilities

Drs. Osama El Shamy and Anna Gaddy, PA Elisha Shelton, and Patient Advocate Michael Phillips discuss the pathophysiology of IgA nephropathy and FSGS, recent advancements in IgA nephropathy and FSGS clinical trials, and the patient experience in FSGS.

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MA-DS-25-0105 | October 2025

Podcast Episode NephrologyIgAN

Insights from the SPARTAN Study

In this episode of the RKD Show, Drs. Jonathan Barratt and Shikha Wadhwani discuss the efficacy, safety, and biomarker findings from the Phase 2 SPARTAN study.

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MA-DS-25-0105 | October 2025

Podcast Episode NephrologyFSGS

From Podocyte to Patient: The Pathophysiology of FSGS

In this episode of the RKD Show, Drs. Tobias Huber and Chris Gisler take a deep dive into the critical role of podocytes in maintaining glomerular function and their central involvement in the development and progression of FSGS.

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MA-DS-25-0105 | October 2025