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The Dual Endothelin Angiotensin Receptor Antagonist (DEARA) Sparsentan Protects From Glomerular Hypercellularity and Associated Immune/Inflammatory Gene-Network- Activity in a Model of IgA Nephropathy
Sparsentan, the dual endothelin and angiotensin receptor antagonist (DEARA), improves kidney function and lifespan and protects against hearing loss in Alport mice with developed renal structural changes
Sparsentan Improves Glomerular Endothelial and Podocyte Functions and Augments Protective Tissue Repair in a Mouse Model of Focal Segmental Glomerulosclerosis (FSGS)