On September 5th, the U.S. FDA granted full approval for our medicine to slow kidney function decline in adults with IgA nephropathy. For more information, see our Press Release.
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Sparsentan, the dual endothelin angiotensin receptor antagonist(DEARA), attenuates albuminuria and protects from thedevelopment of renal injury to a greater extent than losartan inthe gddY mouse model of IgA nephropathy; a 16-week study
Baseline Characteristics of PatientsEnrolled in the Ongoing Phase 3Randomized, Double-Blind, Active-Control Trial of Sparsentan for theTreatment of Immunoglobulin ANephropathy (PROTECT)
The Dual Endothelin Angiotensin Receptor Antagonist (DEARA) Sparsentan Protects From Glomerular Hypercellularity and Associated Immune/Inflammatory Gene-Network- Activity in a Model of IgA Nephropathy
The Dual Endothelin Angiotensin Receptor Antagonist (DEARA) Sparsentan Protects From Glomerular Hypercellularity and Associated Immune/Inflammatory Gene-Network- Activity in a Model of IgA Nephropathy
The Humanistic Burden of Rare Kidney Diseases: Understanding the Impact of Focal Segmental Glomerulosclerosis (FSGS) and Immunoglobulin A Nephropathy (IgAN) on Patients and Caregivers Study (HONUS): Preliminary Results for IgAN in the United States (US)
The Humanistic Burden of Rare Kidney Diseases: Understanding the Impact of Focal Segmental Glomerulosclerosis (FSGS) and Immunoglobulin A Nephropathy (IgAN) on Patients and Caregivers Study (HONUS): Preliminary Results for IgAN in the United States (US)
The Treatment Effect of RAS Blockade on Proteinuria in IgA Nephropathy Patients as a Surrogate for Renal Events and Decline in eGFR: An Analysis of Randomized Controlled Trials